Walking Test Tubes
Drug companies take their trials overseas
July / August 2006
Sonia Shah from NACLA Report on the Americas
Just as automakers and apparel manufacturers have fled the
stringent labor and environmental laws of developed countries to
set up shop in the developing world, pharmaceutical companies have
streamed across borders in pursuit of warm bodies for the testing
of new experimental drugs.
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Drug giant GlaxoSmithKline has predicted that by next year more
than half of its trials will be conducted overseas, a mark already
hit by some of its competitors. In 2004 the U.S. Food and Drug
Administration (FDA) estimated that drug companies angling for
government approval of their products were launching more than
1,600 new foreign trials every year.
The most popular destinations are the broken, impoverished
countries of Eastern Europe and Latin America. In Latin America,
says Pfizer's Julio Camps, 'you can have fast recruitment . . . at
a very reasonable cost.' Populations of patients no longer
available in rich countries-those willing to swallow placebos and
those who have never been treated for their illnesses-abound.
Pfizer's trial of the osteoporosis drug lasofoxifene, for
example, required experimental subjects to be 'treatment-naive,'
that is, never treated for the condition. Argentina was 'the number
one recruiting site,' Camps said, calling the country's ability to
provide willing guinea pigs 'amazing.'
Unlike human subjects in the United States and Western Europe,
who frequently drop out of sometimes unpleasant clinical trials,
Latin America's 'patient retention rates are nearly 10 percent
better' than elsewhere in the world, according to the
clinical-research trade publisher CenterWatch. And they do it for
free: It seems that the provision of medicine, even experimental
medicine, is sufficient.
The industry's new experimental bodies from poor countries
rarely enjoy the benefits of the research they participate in.
Sometimes the new drugs are unlicensed in their countries or priced
out of reach. More often, however, the drugs are irrelevant to the
health priorities of their communities to begin with. Overall, 90
percent of the global medical research budget takes aim at
illnesses that cause just 10 percent of the world's diseases.
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